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A reduction in microbiome diversity has been identified (191), but it is likely that the microbiome composition will differ between ME/CFS patients as each patient has a unique infectious history (193)
The main derivatives of astragalus are methylxanthine, theophylline (1,3-dimethylxanthine), theobromine (3,7-dimethylxanthine), and caffeine (1,3,7-trimethylxanthine) (Li et al., 2017)
They differed by what strength they used
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Insulin-like growth factor 1 signaling in tenocytes is required for adult tendon growth
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