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Baseline characteristics of the patient population in the Saxagliptin Assessment of Vascular Outcomes Recorded in patients with diabetes mellitus (SAVOR)-TIMI 53 trial

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The study of nearly 28,000 23AndMe users who reported taking the weight-loss drugs found that a mutation in GLP1R, the gene for the protein targeted by GLP-1 drugs, is modestly but significantly associated with increased efficacy of the medications, researchers reported in Nature

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Lipids and Cardiometabolic Risk By promoting weight loss, GLP-1 medications can also improve cardiometabolic protection that is, improving heart health by reducing the risk of factors like heart attack and stroke in those without diabetes

the FDA does not review them for safety, effectiveness, or quality before dispensing