We dont have a definitive answer yet, but heres what we do know: Using GLP-1s for at least 12 months improves outcomes Stopping often leads to weight regain
We need to accept people are going to do this whether its safe or not
The country of manufacture is the country where the medication is produced
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some patients report that evening administration may help (though these medications can be administered at any time of day) For constipation: Ensure adequate hydration as tolerated, soluble fiber supplementation (psyllium), osmotic laxatives if needed (polyethylene glycol) For diarrhea: Adequate hydration with electrolyte replacement, continuation of antidiarrheal medications if previously prescribed For bloating: Avoiding carbonated beverages, limiting gas-producing foods, continuing probiotics if previously beneficial Continuation of established IBS therapies is generally appropriate
However, fatigue should not be ignored if it feels intense, continues to worsen, interferes with daily life, or appears alongside other concerning symptoms