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Other pharmacological options include older weight loss medications such as phentermine-topiramate and naltrexone-bupropion, which have different mechanisms of action and may be appropriate for some patients
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Shared neural mechanisms between the food reward system and AUD pathways are well established 6,7,8,9
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Abstract Glucagon-like peptide-1 receptor (GLP-1R) agonists, such as exenatide (Byetta, Bydureon), liraglutide (Victoza, Saxenda), albiglutide (Tanzeum), dulaglutide (Trulicity), lixisenatide (Lyxumia, Adlyxin), semaglutide (Ozempic, Rybelsus, Wegovy), and tirzepatide (Mounjaro, Zepbound), are widely used for the treatment of type 2 diabetes mellitus (T2DM) and obesity
Dosing schedule and titration protocol Semaglutide titration follows a stepped approach designed to minimize gastrointestinal side effects
