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Found in red meat, lentils, spinach

DRUG INTERACTIONS As with other medications, topiramate can interact with alcohol, marijuana and certain medications, including antiepileptic drugs, CNS depressants, oral contraceptives, lithium, other carbonic anhydrase inhibitors, hydrochlorothiazide, pioglitazone and amitriptyline

Blood pressure may begin to decrease in hypertensive patients, and a small increase in heart rate is common

Neurology 97(2):6879 Pemp B et al (2013) Effectiveness of averaging strategies to reduce variance in retinal nerve fibre layer thickness measurements using spectral-domain optical coherence tomography

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