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Few, if any, of these substances have been tested in human trials
Common side effects include pain at the injection site, nausea, and dizziness
Shaking vials vigorously after adding water seems logical but destroys peptides
For individuals with severe B12 deficiency (especially those with anaemia or neurological symptoms), some might start to feel an improvement in their energy levels within a few days to a week
Chloramphenicol, though rarely used in modern practice, can antagonize the hematologic response to vitamin B12 in patients with megaloblastic anemia
Deficiency In healthy adults, overt vitamin B 12 deficiency is uncommon, mainly because total body stores can exceed 2,500 g, daily turnover is slow, and dietary intake of only 2.4 g/day is sufficient to maintain adequate vitamin B 12 status (see The RDA) (4)
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