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Stressed and injured NASH hepatocytes express and secrete a second Hedgehog ligand, Sonic Hedgehog (SHH), which is positively correlated with hepatocyte ballooning, steatosis, pericellular fibrosis, and fibrosis stage in liver samples from NASH patients (206, 207)

Lyophilized form is preferred for long-term storage

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Side Effects : Common issues include gastrointestinal discomfort, which can guide dose adjustments

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Monitor Nutrition Track total calories and hit protein targets