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En personas sanas y a las dosis recomendadas, no se ha asociado de forma consistente con dao renal, deshidratacin ni calambres musculares (2, 3)
Stereospecificity and stereoselectivity of flobufen metabolic profile in male rats in vitro and in vivo: phase I of biotransformation
Common experimental arenas include: Telomere and cellular aging models: Evaluation of telomerase activity, telomere length dynamics, replicative lifespan, and senescence markers in cell culture and animal studies
dissected GLP-1R-expressing lumbar dorsal root ganglion neurons from mice and cultured them with Schwann cell-conditioned media to mimic diabetic conditions ( in vivo experiments, the authors treated the streptozotocin-induced DM mice with exendin-4 at 10 nmol/kg for 4 weeks and found that exendin-4 promoted the peripheral nerve function as reflected by improved current perception threshold and motor and sensory nerve conduction velocity
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