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PATHOPHYSIOLOGY OF DKD Mechanisms of action SGLT2 inhibitors primarily act by blocking SGLT2 located on the luminal membranes of proximal renal tubules (S1 and S2 segments)

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Changes in metabolic parameters and body weight in patients with prediabetes treated with adjunctive brexpiprazole for major depressive disorder: pooled analysis of short- and long-term clinical studies