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In the past few years, there have been reports linking the condition to GLP-1 drugs like semaglutide and tirzepatide

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Early improvement does not always mean lasting change

Published 2018 Dec 5

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Observational real-world data in patients with T2D receiving oral semaglutide for 26 weeks demonstrated preservation of fat-free and skeletal muscle mass despite significant losses in fat mass and visceral adipose tissue, suggesting that the magnitude of lean tissue change may depend on concomitant lifestyle behaviors, such as physical activity and diet [16]