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Sci Rep 5 , 10211 (2015)

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For both, the most common symptoms include nausea, constipation, vomiting, and diarrhoea

90 In the 1970s tamoxifen was one of the first compounds to be tested, but the first public description of the clinical concept of SERMs as useful medicines for womens health was at the First International Chemoprevention meeting in New York, NY in 1987