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Other manufacturers began synthesizing GLP-1 analogs with altered DPP-4 binding sites that bypassed degradation and remained in the body for weeks at a time [26]

11 Place in Therapy In the ADA's 2018 Standards of Medical Care in Diabetes , DPP-4 inhibitors are indicated as an add-on option for patients without clinical atherosclerotic CV disease (ASCVD) who are unable to reach goal A1C after taking metformin for 3 months

Keeping hydrated also decreases the risk of bruising from an injection

Always Take with Food A small meal or snack before your capsule significantly reduces the chance of stomach upset

They are not medical-use, diagnostic, or treatment claims