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Jeong et al., 2013
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Its a naturally occurring peptide made of three essential amino acids glycine, cysteine and glutamic acid
![glp 1 fisiologia Mechanism of action of GLP-1 [25] GLP-1, MSCULO Y METABOLISMO Lo](https://media.licdn.com/dms/image/v2/D4E12AQES6d89Ei7Uzw/article-cover_image-shrink_720_1280/article-cover_image-shrink_720_1280/0/1723928979684?e=2147483647&v=beta&t=T92iJ6YhDvoglp-glPLO_ewE_l2UW0U1gCkIBzFnIh8)
If progress stalls after you reach maintenance, that's worth a conversation with your clinician about dose, diet, and other factors
![glp 1 fisiologia Mechanism of action of GLP-1 [25] GLP-1, MSCULO Y METABOLISMO Lo](https://pancreapedia.org/sites/default/files/Figure%202_Williams.png)
Path 2: Gradual taper and discontinuation For patients who have made substantial lifestyle changes and want to attempt life without medication, a structured taper offers the best chance of success
![glp 1 fisiologia Mechanism of action of GLP-1 [25] GLP-1, MSCULO Y METABOLISMO Lo](https://upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Incretins_and_DPP_4_inhibitors-es.svg/1280px-Incretins_and_DPP_4_inhibitors-es.svg.png)
Mathur, M
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Moving the dinner time NPH injection to bedtime can also decrease insulin stacking, and lower the risk of nocturnal hypoglycemia
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