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Debido a que la fosfatidilcolina es necesaria para la sntesis de partculas de lipoprotenas de muy baja densidad (VLDL) (ver Funcin), la deficiencia de colina produce una secrecin alterada de VLDL y acumulacin de grasa en el hgado (esteatosis), lo que en ltima instancia conduce a dao heptico