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Cheema and colleagues had conducted research into whether GLP-1 receptor agonists may benefit people with polycythemia vera or myelodysplastic syndrome

Effect sizes for heavy drinking days and drinks per drinking day were medium to large

Front Public Health 10:960965

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10.1002/dmrr.2502 122

Pegylation extends that window by attaching a polyethylene glycol chain to the peptide backbone, slowing renal clearance and giving researchers a longer usable window for site-specific study designs without eliminating the localized character of the response