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Ozempic (semaglutide) is FDA-approved for type 2 diabetes treatment but may be prescribed off-label for weight loss at a healthcare providers discretion

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Nature 575(7783):505511

Some people are just less interested in food overall (Mozafariun 2025)

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However, in phase 3a trials, mean baseline Patient Health Questionnaire-9 (PHQ-9) scores for liraglutide vs placebo improved at the treatment end