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Eligibility in India generally means a BMI of 2730 with a metabolic complication (such as PCOS, fatty liver, or prediabetes) or a BMI above 30, alongside uncontrolled Type 2 diabetes, abdominal obesity, or strong family history of metabolic disease
Obesity as disruptor of the female fertility
Others prefer evening injection, hoping to sleep through the initial adjustment window
274,275 This, in turn, diminishes additional downstream effects, including oxidative stress, the secretion of pro-degradative substances, modifications to cell phenotype (hypertrophy, M1/M2 macrophage phenotype, fibrosis), and damage or deterioration of joint cells (apoptosis, senescence)
Preclinical studies have validated the therapeutic potential of these compounds for the treatment of obesity and diabetes
doi: 10.1016/S0261-5614(17)30566-6 41
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