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For interventions, stage-specific combination therapies should be designed for the 672-h secondary-injury window
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Some people combine the 2, but for most, NAC alone is the more cost-effective way to support glutathione levels
Pickart L, et al
doi: 10.1002/ana.26134 218
In fact, the addition of NBDHEX, a strong and specific inhibitor of e-GST and other GST isoenzymes belonging to the alpha, pi and mu classes, 13 did not suppress this additional GST activity (Figure 2b), and curiously the activity was also found in the absence of GSH (Figure 2a)
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