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doi: 10.1016/S0021-9258(18)67324-7 23 HolstJJOrskovCNielsenOVSchwartzTW
Diabetes Ther 12 , 879896 (2021)
After one year: Continued max dose: weight loss essentially fully maintained Stepped down to 5 mg: weight loss largely maintained, with an average regain of about 12 pounds Switched to placebo: large regain, with roughly 67% of patients eventually requiring rescue therapy That 12-pound tradeoff is the answer to the question patients ask most often: What does it actually cost me to step down
4 and 5, Extended Data Fig
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