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Critically, perioperative metabolic reprogramming is driven by acute DAMPs/mtDAMPs exposure, ischemia-reperfusion-induced hypoxia/reoxygenation, and the inflammatory cytokine milieunot by oncogenic transformation

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If the half-life is genuinely under 30 minutes, the compound is cleared too rapidly

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Front Endocrinol (Lausanne) (2019) 10:492

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