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GLP-1 medications often lead to weight loss of 1525% within the first year, with most people reaching their peak loss around 36 weeks

Once administered, it binds to GLP-1 receptors throughout your body, triggering several physiological responses: Pancreatic effects : Stimulates insulin secretion when blood glucose levels are elevated and suppresses glucagon release, helping to normalize blood sugar Gastric effects : Slows gastric emptying, meaning food stays in your stomach longer, promoting feelings of fullness [1] [2] Central nervous system effects : Acts on appetite centers in the brain to reduce hunger and food cravings Cardiovascular benefits : Reduces the risk of major adverse cardiovascular events in adults with established cardiovascular disease and overweight/obesity (Wegovy) or type 2 diabetes (Ozempic) [5] [6] The medication has a long half-life of approximately one week, which allows for once-weekly subcutaneous injection

Mild digestive discomfort: Cramping or slight indigestion can occur as the body recalibrates digestion processes

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Frequently asked questions How do GLP-1 patches work for weight loss

If youre eating food but not drinking enough, you can develop hard stools that are painful to pass