For significant obesity or obesity-related health conditions, surgery remains the most effective long-term treatment by a wide margin
GLP-1 agonists like semaglutide mimic a natural hormone called GLP-1 that regulates appetite and glucose levels in the body, which can help manage obesity and promote weight loss
As of the time of writing, retatrutide has not been approved by the MHRA or the EMA for any indication
Cagrilintide + tirzepatide swaps semaglutide for tirzepatide, which adds GIP receptor activity
Some people experience fishy aftertaste or mild GI discomfort
amycretin Novo Nordisk, which makes Wegovy and Ozempic, is testing this experimental, unimolecular drug to target two hormone pathways, GLP-1 and amylin, a hormone that helps control hunger