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Another explanation for metformins wide-ranging benefits has more recently gained recognition: its ability to impact the gut and the intestinal microbial community (microbiome) (McCreight 2016
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Considering the fact that Baf-A1 suppresses fusion of autophagosomes with the lysosomes 39 , our finding that DFO protected against ferroptosis suggests that lysosomal iron pool is involved in GSH depletion-induced cell death 48
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