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Diet-induced obese mice were switched from an obesity-promoting diet to a lower-fat diet and compared with groups receiving diet change alone or diet change plus 5-Amino-1MQ

At typical subcutaneous doses of 1-3 mg/day, the copper contribution is small relative to dietary intake (the recommended daily allowance is 0.9 mg elemental copper per the National Institutes of Health Office of Dietary Supplements) 8

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