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Metabolic and Bariatric Surgery (MBS) Source: Barrett, et al JAMA Surgery, September 17, 2025 Implications for employers: Bariatric surgery costs less than GLP-1 medications, and is likely more effective at inducing weight loss than older GLP-1 agents, which are not usually used for weight loss at this point

The Most Commonly Reported Ones Include Gastrointestinal Symptoms Such as Nausea, Vomiting, Diarrhea, Constipation, and Abdominal Discomfort

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Finding semaglutide stomach pain relief involves controlling digestion, hydration, and food choices while your body adapts

J Neurosci 30 , 1639116398 (2010)

Microdose semaglutide may also be useful for patients who want to test tolerability before moving into a standard-dose pathway