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The available X-ray crystal structures implicate histidine 571 (that arises from the opposing subunit) as being responsible for this deprotonation, as it is the only residue that is proximal to the C154-C159 pair that has the capacity to act as a general base (Figure 2)

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This is how this format differs from the classic lyophilisate vial: the researcher does not dissolve a dry powder but instead receives an already-prepared working solution, with the concentration and number of units recorded in the batch COA