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SF (1.25 or 2.5 M treated for 48 h) upregulated Nrf2 expression and facilitated Nrf2 nuclear translocation by reducing DNA methylation of the Nrf2 promoter in a cellular AD model (69)
These challenges may limit patient access to beneficial therapies
Yasir et al., 2015)
While head-to-head clinical trials are limited, available data provides valuable insights into their relative efficacy, safety, and clinical utility
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