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Clinical trial data from SURMOUNT-1 shows that musculoskeletal complaints did not occur at significantly higher rates in the tirzepatide group compared to placebo
It is also worth noting that hormonal contraception (such as the combined pill or a hormonal intrauterine system) can cause absent or very light periods independently of energy status, which may mask cycle changes related to low energy availability
Elliott RM, Morgan LM, Tredger JA, Deacon S, Wright J, Marks V
The GLP-1 market is projected to reach $347.5 million by 2035, growing at a 17.8% CAGR
For those who plateau at 1.0 mg or need greater appetite suppression, 1.7 mg provides a meaningful step up
It is currently in Phase 3 for alcohol use disorder (the RENEW-ALC-1 and RENEW-ALC-2 trials, 1,100 patients each) and in earlier-stage development for bipolar disorder, major depressive disorder, smoking withdrawal, asthma, cardiovascular and liver disorders, and obesity
