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Lipids provide a rather strong stimulus for GLP-1 secretion (63), and in this connection it is of interest that L-cells were recently reported to express a deorphanized G protein-coupled receptor for long-chain saturated fatty acids, GPR120 (112)

Both insulin Signaling Defects in the Liver and Obesity Contribute to Insulin Resistance and Cause Diabetes in Irs2(-/-) Mice

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Smaller portions place less mechanical stress on an already slower-emptying stomach

In 28-month-old mice, roughly equivalent to elderly humans, three weeks of GHK-Cu administration produced significantly faster maze navigation with evidence of decreased brain inflammation and increased histone deacetylase 2 labeling, an indicator of epigenetic pathway activation

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