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1,2 In recent years, incretin-based therapiessuch as semaglutide and tirzepatidehave received FDA approval for several indications, including type 2 diabetes and weight management, potentially impacting the overall obesity trends in the US
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In Cohort 1, 25 WT and 25 RAMP1/3 KO male mice aged 1220 weeks old were injected intraperitoneally after a 12-hour fast with vehicle, sCT at doses of 3 or 150 nmol/kg, or Cagrilintide at a dose of3 nmol/kg
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