While PDE5 inhibitors can cause headaches, vision changes, and digestive issues, PLC typically has fewer side effects
398(10295): p
Many authors report this capacity to recognize and transport several types of anti-cancer drugs such as doxorubicin with high affinity (Okabe et al., 2005)
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Under hypoxic or ER stress conditions, ATF4 upregulates BH3-only proteins such as HRK, PUMA , and NOXA , which influence mitochondrial integrity and autophagy
Whether it produces similar carcinogenic effects in humans is unknown, and can not be ruled out with available data