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The presence of alpha-aminoisobutyric acid (Aib), D-2-naphthylalanine, and D-phenylalanine gives it a non-standard amino-acid signature that is readily distinguishable from Tesamorelin by reverse-phase HPLC retention behavior, UV absorbance from the naphthyl chromophore, and mass spectrometric fragmentation patterns, making the Tesamorelin + Ipamorelin blend a convenient dual-analyte reference for orthogonal separation and detection method work
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All methods were performed in accordance with the guidelines and regulations of the Animal Care and Use Committee of Wenzhou Medical University and Ethics Committees of Wenzhou Medical University
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Lingvay, I., Desouza, C
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