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JAMA 282:15681575 Clemmensen C, Chabenne J, Finan B et al (2014) GLP-1/glucagon coagonism restores leptin responsiveness in obese mice chronically maintained on an obesogenic diet

Access this article Similar content being viewed by others Abbreviations GSH: l--glutamyl-l-cysteinyl-glycine (glutathione) GSSG: Oxidised form of glutathione DEM: Diethylmaleate H 2 S: Hydrogen sulfide IL-6: Interleukin-6 JNK: c-Jun- N -terminal kinase MAPK: Mitogen-activated protein kinase NF-B: Nuclear factorB SAPK: Stress-activated protein kinase TNF: Tumour necrosis factor xCT: Subunit of the x c cystine-glutamate exchanger References Aitken SM, Kirsch JF (2005) The enzymology of cystathionine biosynthesis: strategies for the control of substrate and reaction specificity

All following values are presented as least square (LS) means of the group by time interaction with additional standard errors

Moore has maintained a close eye on the evolution of the drugs, from lawsuits filed by manufacturers over compounded replicates to clinical trials of newer GLP-1 options at CU Anschutz

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