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The key takeaway is that GHK-CU produces measurable, documented improvements when used consistently at appropriate doses

PMC review 2025 Clinical Trial Results: What the Data Actually Shows This is the section that matters most

The effect is almost exclusively from the CJC-1295 component of the stack

Patients who experience early nausea sometimes find that evening dosingtimed 23 hours after their last mealallows the medication to settle without competing with hunger signals during eating times

Thus, vitamins were not prescribed to such patients

Since it is not completely neutral in pH, it can cause irritation, he says