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There are no other absolute contraindications reported for hydroxocobalamin use in deficiency states, but caution is advised in individuals with conditions such as early Lebers optic neuropathy (a rare hereditary optic atrophy) due to the theoretical risk of worsening vision

At the same time, inhibiting NNMT also helps preserve another important molecule: S-Adenosyl Methionine (SAM)

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References (1) Pissios P

Il prodotto viene conferito dai soci nellimpianto di confezionamento e stoccaggio dove possibile iniziare subito la lavorazione, il confezionamento e la catena del freddo

For vitamin B deficiency (e.g., pernicious anemia), a common regimen is to begin with frequent intramuscular injections to replenish body stores