It is under investigation in preclinical and clinical studies on overweight, obesity, and metabolic disorders, where researchers have examined its effects on body weight and energy intake, including when combined with GLP 1 receptor agonists such as semaglutide, but it is not an approved therapy
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Animals were single-housed before the operation and allowed to recover for 4 wk before the start of treatment
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The researchers observed a more pronounced risk of vision impairment when comparing semaglutide with other antidiabetic medicines, including dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT2) inhibitors, and metformin
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