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Semaglutide Side Effects: Nausea 30-40% of patients (usually mild, improves within 2-4 weeks) Diarrhea 20-30% of patients Constipation 10-15% of patients Vomiting 5-10% of patients Decreased appetite expected and desired effect Fatigue 5-10% of patients Tirzepatide Side Effects: Nausea 25-35% of patients (can be more intense initially) Diarrhea 20-25% of patients Decreased appetite stronger than semaglutide Vomiting 10-15% of patients Constipation 10-15% of patients Acid reflux 5-10% of patients How to Minimize Side Effects: At Majestic Aesthetics, we use a gradual dosing strategy to minimize side effects: Start low Begin at the lowest dose and increase slowly Increase gradually Bump up dose every 4 weeks as tolerated Take with food Inject after a meal if nausea occurs Stay hydrated Drink plenty of water throughout the day Eat smaller meals Large meals can trigger nausea Communicate Tell us about side effects so we can adjust your dose Most side effects improve significantly within 3-4 weeks as your body adjusts to the medication

Semaglutide belongs a class of drugs called glucagon-like peptide-1 receptor agonists (GLP-1RAs) that mimic GLP-1 protein produced naturally by our bodies

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Abnormal pulmonary function in COVID-19 patients at time of hospital discharge

Nausea and appetite effects usually fade over days to weeks, but gallstone symptoms depend on anatomical changes

It's FDA-approved for chronic weight management