Sec24 is a critical COPII component responsible for cargo selection in the process of ER-to-Golgi trafficking [23]
Our results provide a possible mechanism in which upregulation of phosphorylated p53 and p16 maintain the cell cycle arrest of keloid fibroblasts, and FOXO4-DRI selectively induces apoptosis of keloid senescent fibroblasts by prompting p53-pS15 nuclear exclusion
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signs like rash, itching, or swelling would necessitate immediate medical attention