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Furthermore, there may be concerns regarding the long-term safety profile and uncommon adverse effects associated with GLP-1 receptor agonists, which may limit their use in specific patient populations

However, he did single out a few factors that may contribute to increased risk

Nanomedicine (2017) 13(2):65965.10.1016/j.nano.2016.08.004 87 GuanLGongDTianNZouY

Bachmeyer claims is the first step in preventing systemic disease

Clinical implication Clinicians are encouraged to perform comprehensive evaluations prior to prescribing GLP-1 RA therapy in patients with a history of pancreatic disorders or other pancreatitis risk factors