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The gut

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Reimann F, Diakogiannaki E, Hodge D, Gribble FM

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The most commonly used peptides in longevity medicine include growth hormone secretagogues like sermorelin and ipamorelin (for muscle preservation and sleep), BPC-157 (for tissue repair), thymosin alpha-1 (for immune function), and GLP-1 receptor agonists like semaglutide (for metabolic health)

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The anti-inflammatory effects and observed improvement in psoriasis and HS after GLP-1RA treatment opens the possibility of studying their therapeutic potential in other common inflammatory skin conditions such as bullous pemphigoid, lupus erythematosus, and atopic dermatitis

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Among these, glucagon-like peptide-1 (GLP-1) receptor agonists, which are already approved for weight management and type 2 diabetes, have shown promise

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While gastrointestinal effects are well-documented, a growing number of patients and clinicians have begun discussing anxiety a side effect less talked about but increasingly relevant as these therapies expand

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