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Absorbed vitamin B 12 is transported via specific B 12 binding proteins, transcobalamin I and II to the various tissues
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In cell culture studies, -tocopherol was found to improve the formation of an adhesive junction (known as immune synapse) between nave T lymphocytes and antigen presenting cells (APC), which eventually prompted T cell activation and proliferation (see Disease Prevention) (6, 7)
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rather, it is one of the manifestations of protein misfolding which may result from partially folded polypeptides that fail to achieve their native stable conformation or aggregation of native protein which has less solubility [23]
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