Starting with lower GLP-1 doses and gradually adapting to the ketogenic diet may improve tolerance
Cenci A, Macchia I, La Sorsa V, Sbarigia C, Di Donna V, Pietraforte D
The bottom line GLP-1 drugs are not a replacement for insulin, and they are not officially approved for T1D (outside of the new 2026 ADA recommendation for T1D with obesity)
She Started the GLP-1 Microdosing Conversation
Consistently, a complementary strategy showed that in aged mice, where IGF-I levels are decreased, cardiac overexpression of IGF-I significantly improved cardiomyocyte contractile function[283], attenuating oxidative stress-mediated protein damage, normalizing Ca 2+ homeostasis, reversing age-related alterations in the expression of pro-apoptotic proteins, and decreasing the apoptosis rate[284]
Make high-protein swaps