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The references above are single-compound or class-level studies.
Yoon KH, Kang J, Kwon SC, et al
cardiac reasons are rarely the cause but should always be considered
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For researchers prioritizing muscle preservation, a moderate dose of 4 to 8 mg combined with adequate protein intake (1.0 to 1.2 grams per kilogram of body weight) and resistance training appears to optimize the fat-to-lean mass loss ratio
2 This is a cost-effectiveness recommendation, not a safety threshold: private prescriptions have no equivalent cap
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