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For systemic benefits, oral GHK-Cu can't match injection due to substantial enzymatic degradation in the GI tract

[1] [3] The dosing regimen for Ascorbic Acid (Vitamin C) Injection should be individualized based on the patients clinical condition, severity of deficiency, and therapeutic goals

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We first studied hyperpolarized [1- 13 C]dehydroascorbate in the normal rat brain, demonstrating its robust conversion to [1- 13 C]vitamin C, consistent with rapid transport of the oxidized form across the blood-brain barrier

10.1523/JNEUROSCI.3885-07.2007 20 ChoiI