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Patients taking medications that can cause hypoglycaemia (such as when GLP-1 therapy is combined with insulin or sulfonylureas) should follow DVLA 'Assessing fitness to drive' guidance, including appropriate glucose monitoring before and during driving

clinical endpoints are therefore hypothesis-generating

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In comparison with GLP-1 RAs, no significant difference was observed in the post-intervention HDL cholesterol with SGLT2is (WMD: 0

However, their use is not universally appropriate, as certain medical conditions and personal histories may contraindicate treatment

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