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The team also noted hexarelins activity at the scavenger receptor CD36, highlighting its cardioprotective potential [2]

doi:10.1586/1744666X.2.5.665 Chaudhary V, Bano S

Gastrointestinal Cytoprotection In its original gastric biology context, BPC-157 promotes mucosal integrity through prostaglandin-independent mechanisms, modulates enteric neuron and glial cell activity, counteracts NSAID-induced intestinal permeability, and demonstrates organoprotective activity across the alimentary canal from oesophagus to colon in a range of injury models including ethanol, aspirin, and restraint stress-induced lesions

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That distinction matters for understanding why systemic IGF-1 LR3 administration and local MGF activity are not equivalent in their biological targets, even though both ultimately activate many of the same downstream signalling nodes