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First, it acts as a vehicle of copper, an element essential for multiple enzymes responsible for connective tissue formation, antioxidant activity, and cellular respiration

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At the same time, the nerves to the muscles are hyperexcitable, leading to tremor, tics, jerks, spasm and twitching, and jumping at the smallest stimulus

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These data indicate that genes associated with metabolic ROS generation tend to be upregulated in MZB compared to FoB, suggesting that differences in the control of ROS signaling might contribute to the classical distinctions between these two mature B cell subsets