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GLP-1 RAs improve CV outcomes, as well as secondary outcomes such as progression of renal disease, in patients with established CV disease or chronic kidney disease (CKD)
These combined effects are particularly intriguing for orthopedics because many musculoskeletal injuries (Achilles tendon ruptures, rotator cuff tears, chronic tendinopathies) occur in precisely those areas where blood flow is limited and healing is frustratingly slow
Journalist Sara Talpos wrote an excellent expos on peptides in Undark, revealing intriguing facets of peptide-based therapies such as BPC-157, including their history and applications
That is why it can be swallowed at all, and why it behaves like a small-molecule drug: real oral absorption, first-pass liver metabolism, a huge volume of distribution (39 L/kg in mice), and off-target enzyme binding
It is also found in foods such as meats, fish, nuts, beans, spinach and eggs
So, theres a pretty good chance you wont realize how drunk you are (or that its time to stop drinking )
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