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Pattern 1: sudden gain of 3 to 7 pounds over 1 to 2 days Most likely cause: Water retention

However, growing evidence indicates that alternative metabolic routes such as malic enzyme 1 (ME1), isocitrate dehydrogenases (IDH1 and IDH2), and the folate cycle also significantly contribute to NADPH production, particularly under stress conditions or during metabolic reprogramming [43]

cant wait for couple of months to go by and continue to see improvements in my dark blemishes

10.1016/0361-9230(84)90190-4 112 WiseR

Tanada et al., 2023)

Current research of these lesions is limited due to the scarce number of cases reported in the literature, which is no surprise given the rarity of these tumors