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Dimethoxycurcumin, a synthetic curcumin analogue, induces heme oxygenase-1 expression through Nrf2 activation in RAW264.7 macrophages

The metabolic pathways of new drugs should be determined to predict the possibility of adverse drug reactions and drug-drug interactions

Unlike drugs that target a single pathway, GHK-Cu acts as a bioregulatory molecule, supporting a wide range of cellular processes

The concentration will be higher than intended

MACE, kidney composite, and biopsy-confirmed liver histology are clinically actionable

Oral lesions presented each as an asymptomatic pigmented dark-brown macule with an intact mucosal surface and well-defined borders, except case 2